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Nephrology Xagena

Reduction of dietary sodium intake or diuretic treatment increases renin-angiotensin-aldosterone system ( RAAS ) blockade efficacy in non-diabetic nephropathy. A study has investigated the effect of ...


Risk of end-stage renal disease ( ESRD ) in kidney donors has been compared with risk faced by the general population, but the general population represents an unscreened, high-risk comparator. A co ...


Peritoneal dialysis is the renal replacement therapy of choice for acute kidney injury in neonates, but in some cases is not feasible or effective. Continuous renal replacement therapy ( CRRT ) machin ...


The two largest studies of mammalian target of rapamycin inhibitor treatment of autosomal dominant polycystic kidney disease ( ADPKD ) have demonstrated no clear benefit on the primary endpoint of tot ...


In autosomal dominant polycystic kidney disease ( ADPKD ), progressive kidney cyst formation commonly leads to end-stage renal disease ( ESRD ). Because important manifestations of ADPKD may be evid ...


The role of hyperuricemia in disease progression of autosomal dominant polycystic kidney disease ( ADPKD ) has not been defined well. Researchers have investigated the association of serum uric acid ...


Autosomal dominant polycystic kidney disease ( ADPKD ) is a major cause of end-stage kidney failure, but is often identified early and therefore amenable to timely treatment. Interventions known to ...


New-onset diabetes after transplantation ( NODAT ) is a common complication after renal transplantation. There are limited available oral drugs to treat hyperglycaemia in this population owing to redu ...


Atherosclerotic renal-artery stenosis is a common problem in the elderly. Despite two randomized trials that did not show a benefit of renal-artery stenting with respect to kidney function, the useful ...


Abdominal aortic calcification ( AAC ) is reported as a predictor for cardiovascular events in general population and in hemodialysis patients. At present, there are no AAC data in peritoneal dialysis ...


Tolvaptan ( Samsca ), a diuretic with a new mechanism of action, selectively binds to the vasopressin V2 receptor and inhibits reabsorption of water. Its effect on heart failure is proven, but its ben ...


Tolvaptan ( Samsca ), a diuretic with a new mechanism of action, selectively binds to the vasopressin V2 receptor and inhibits reabsorption of water. Its effect on heart failure is proven, but its ben ...


Contrast-induced nephropathy ( CIN ) is a frequent complication of many radiological procedures involving the application of contrast media. It represents a significant health problem that causes the ...


Combination therapy with angiotensin-converting–enzyme ( ACE ) inhibitors and angiotensin-receptor blockers ( ARBs, sartans ) decreases proteinuria; however, its safety and effect on the progression o ...


Levels of a protein in the urine of kidney transplant recipients can distinguish those at low risk of developing kidney injury from those at high risk. The results also suggest that low levels of this ...


Results from the FIND-CKD study were presented at the American Society of Nephrology ( ASN ) Kidney Week in Atlanta, Georgia, USA. The FIND-CKD results have shown that Ferinject ( Ferric carboxymaltos ...


Vasopressin V2-receptor antagonists may delay disease progression in autosomal dominant polycystic kidney disease ( ADPKD ). Trials with V2-receptor antagonists have been performed predominantly i ...


Peginesatide, a synthetic peptide-based erythropoiesis-stimulating agent ( ESA ), is a potential therapy for anemia in patients with advanced chronic kidney disease.Researchers have conducted two rand ...


The FDA ( Food and Drug Administration ) has advised healthcare professionals of significant liver injury associated with the use of Samsca ( Tolvaptan ). In a double-blind, 3-year, placebo-controlled ...


Individuals with the autoimmune disease systemic lupus erythematosus ( SLE ) can experience a number of medical complications, such as lupus nephritis, an inflammatory kidney disorder. Lupus affec ...



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