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Nephrology Xagena

New-onset diabetes after transplantation ( NODAT ) is a common complication after renal transplantation. There are limited available oral drugs to treat hyperglycaemia in this population owing to redu ...


Atherosclerotic renal-artery stenosis is a common problem in the elderly. Despite two randomized trials that did not show a benefit of renal-artery stenting with respect to kidney function, the useful ...


Abdominal aortic calcification ( AAC ) is reported as a predictor for cardiovascular events in general population and in hemodialysis patients. At present, there are no AAC data in peritoneal dialysis ...


Metanephric adenoma is a rare renal neoplasm, accounting for 0.2% of adult renal epithelial neoplasms. It is usually benign and was first described by Brisigotti et al [ Histol Histopathol 1992 Oct;7( ...


Hyperphosphataemia is a known independent risk factor for cardiovascular mortality. The objective of the study was to compare the effects of two phosphate binders, Sevelamer carbonate ( Renvela ) and ...


Tolvaptan ( Samsca ), a diuretic with a new mechanism of action, selectively binds to the vasopressin V2 receptor and inhibits reabsorption of water. Its effect on heart failure is proven, but its ben ...


Tolvaptan ( Samsca ), a diuretic with a new mechanism of action, selectively binds to the vasopressin V2 receptor and inhibits reabsorption of water. Its effect on heart failure is proven, but its ben ...


Endothelial dysfunction underlies multiple cardiovascular consequences of chronic kidney disease ( CKD ) and antecedent diabetes or hypertension. Endothelial insults in chronic kidney disease or end-s ...


Contrast-induced nephropathy ( CIN ) is a frequent complication of many radiological procedures involving the application of contrast media. It represents a significant health problem that causes the ...


Membranous nephropathy leads to end-stage renal disease in more than 20% of patients. Although immunosuppressive therapy benefits some patients, trial evidence for the subset of patients with declinin ...


Combination therapy with angiotensin-converting–enzyme ( ACE ) inhibitors and angiotensin-receptor blockers ( ARBs, sartans ) decreases proteinuria; however, its safety and effect on the progression o ...


Levels of a protein in the urine of kidney transplant recipients can distinguish those at low risk of developing kidney injury from those at high risk. The results also suggest that low levels of this ...


Results from the FIND-CKD study were presented at the American Society of Nephrology ( ASN ) Kidney Week in Atlanta, Georgia, USA. The FIND-CKD results have shown that Ferinject ( Ferric carboxymaltos ...


Vasopressin V2-receptor antagonists may delay disease progression in autosomal dominant polycystic kidney disease ( ADPKD ). Trials with V2-receptor antagonists have been performed predominantly i ...


Peginesatide, a synthetic peptide-based erythropoiesis-stimulating agent ( ESA ), is a potential therapy for anemia in patients with advanced chronic kidney disease.Researchers have conducted two rand ...